IFITM2 specific antibody
Volume : 100 µg
Purification : Protein A+G purification
Form : liquid
Purity : 95% as determined by SDS-PAGE
Host : Mouse
Clonality : monoclonal
Clone ID : 9C2
Isotype : IgG1
Storage : PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background : IFN-induced antiviral protein which inhibits the entry of viruses to the host cell cytoplasm, permitting endocytosis, but preventing subsequent viral fusion and release of viral contents into the cytosol. Active against m µLtiple viruses, including influenza A virus, SARS coronavirus(SARS-CoV), Marburg virus(MARV), Ebola virus(EBOV), Dengue virus(DNV), West Nile virus(WNV), human immunodeficiency virus type 1(HIV-1) and vesic µLar stomatitis virus(VSV). Can inhibit : influenza virus hemagglutinin protein-mediated viral entry, MARV and EBOV GP12-mediated viral entry, SARS-CoV S protein-mediated viral entry and VSV G protein-mediated viral entry. Induces cell cycle arrest and mediates apoptosis by caspase activation and in p53-independent manner.
Immunogen : interferon induced transmembrane protein 2
Aliases : DSPA2c, IFITM2
Observed MW : 15 kDa
Uniprot ID : Q01629
Reactivity : Human
Application : ELISA, WB, FC
Recommended dilution : WB : 1 : 500 - 1 : 2000
Gene ID :
Research Area : Immunology