T2R45 rabbit pAb - 50 μL

Function: Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5. miscellaneous: Most taste cells may be activated by a limited number of bitter compounds; individual taste cells can discriminate among bitter stimuli. similarity: Belongs to the G-protein coupled receptor T2R family. tissue specificity: Expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells.