p140Cap rabbit pAb - 100 μL

Function: Delays the onset of cell spreading in the early stages of cell adhesion to fibronectin. Also involved in calcium-dependent exocytosis from PC12 cells. PTM: Tyrosine-phosphorylated in response to EGF and to cell adhesion to integrin ligands. similarity: Belongs to the p140Cap family. subcellular location: Localized to the perinuclear region, lamellopodia, cortical actin and actin stress fibers but not to focal adhesions. subunit: Interacts with the N-terminal coiled-coil region of SNAP25 (By similarity). Interacts with BCAR1/p130Cas through its C-terminal domain.