SYCP1 rabbit pAb - 50 μL

Domain: Consists of an alpha-helical stretch of 700 AA residues, flanked by N- and C-terminal globular domains. The C-terminal domain has DNA-binding capacity. function: Major component of the transverse filaments of synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase. subcellular location: In tripartite segments of synaptonemal complexes, between lateral elements in the nucleus. Found only where the chromosome cores are synapsed. Its N-terminus is found towards the center of the synaptonemal complex while the C-terminus extends well into the lateral domain of the synaptonemal complex. subunit: Found in a complex with SYCE1 and SYCE2. Interacts with SYCE1 and SYCE2. tissue specificity: Testis.